The District of Columbia leads with the highest share of people employed in science, technology, engineering, and math.
Massachusetts, home to innovative schools like MIT, ranks second in innovation, with its tech sector contributing nearly 13% of the state's gross product.
WalletHub compared the 50 states and the District of Columbia across 25 key indicators of innovation-friendliness.
The U.S. spends more than $800 billion per year on research and development.