Which states are losing the most people to fentanyl?

In 2022, West Virginia had the highest rate of age-adjusted fentanyl overdoses of any state, at 67 deaths per 100,000 people, 42.3% higher than Delaware, with the next highest rate of 47.1. West Virginia was home to seven of the 10 counties with the highest fentanyl overdose rates, based on 2022 county-level CDC data.

South Dakota had the lowest rate of fentanyl overdoses, with 4.6 deaths per 100,000 residents.

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