The Drugs Earning the Most Medicare Dollars in America - Voronoi
Oct 26, 2025
The Drugs Earning the Most Medicare Dollars in America
Key Takeaways
America's most common drug, Eliquis (generic name: Apixaban) is a blood thinner, indicating how, aging (along with obesity and high-priced biologics) is reshaping Medicare spending.
In fact, five of the top 10 drugs treat diabetes. Three of the top 35 diabetes medications are also approved for weight loss.
And these new GLP-1s are pricey: Ozempic/Mounjaro/Trulicity all come in at $356–$540 per dose.
Then there are rare-disease drugs that earn more per patient versus the more common medications.
For example, Stelara gets around $3B in Medicare spending from 23,000 patients, treating various kinds of arthritis.
On the other hand, Arexvy (a vaccine to prevent RSV, a kind of viral infection,) receives $1.4B from 4.4M people,
