Where Data Tells the Story
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This map shows the number of incorporated areas (aka cities) with 250,000+ residents in each state.
While big cities we're familiar with all have a central city, they often have suburbs which at their own distinct incorporated areas as well. This can lead to interesting results in the final count. For example, Nevada has two main population centers: Las Vegas and Reno. The reason there are four cities shown for Nevada in the map above is because two of Las Vegas' suburbs, Henderson and North Las Vegas, each have populations that crack the 250K mark.
Conversely, in South Carolina, we end up with no cities listed. The state's urban areas are divided up in such a way that none of them (including the central cities of Charleston, Columbia, and Greenville) end up passing 250K in population.